Targets dynamic expression lines
$39.00 30 mL
★★★★★From Amazon reviews“Impressive Copper Peptide Serum”Rafael·“My best buy”Hassam Usmani·“Solid peptide-packed serum that lightweight and layers easily”Juan Garcia·“Clearer skin after 10 days, niacinamide, copper peptides and more, not irritating to skin”Sarah·“POISELLE Copper Peptides Serum for Face”dusksi·“Impressive Combination of Peptides in One Serum”Worldgroup SysOp·“Great serum packed with a lot of skin benefiting ingredients!”Amazon Customer·“So far so good”Ashley·“Hydrating Serum That Fits Easily Into My Routine”Trying Stuff Since 2022·“Copper Peptide Serum”Amazon Customer·“Effective peptide serum with great texture and ingredients”T-Rock·“Great serum, even for sensitive skin”Abee Ward·“Packed serum”LCB·“This serum has been fantastic for keeping my skin hydrated and looking smoother!”Lilly Sky·“Good”ZuLaNi·“lightweight texture, skin doesn't feel greasy after use”Sarah Stewart·“Hydrating Peptide Serum That Makes Skin Feel Smoother”Cheesasaurus Rex·“Moisturizing”Level Up·“Nice and moisturizing”K·“Good for aging skin”C.A.H.·“Feels soothing and nourishing”SonomaGal·“Has a slight effect, so far.”Lance C.·“Impressive Copper Peptide Serum”Rafael·“My best buy”Hassam Usmani·“Solid peptide-packed serum that lightweight and layers easily”Juan Garcia·“Clearer skin after 10 days, niacinamide, copper peptides and more, not irritating to skin”Sarah·“POISELLE Copper Peptides Serum for Face”dusksi·“Impressive Combination of Peptides in One Serum”Worldgroup SysOp·“Great serum packed with a lot of skin benefiting ingredients!”Amazon Customer·“So far so good”Ashley·“Hydrating Serum That Fits Easily Into My Routine”Trying Stuff Since 2022·“Copper Peptide Serum”Amazon Customer·“Effective peptide serum with great texture and ingredients”T-Rock·“Great serum, even for sensitive skin”Abee Ward·“Packed serum”LCB·“This serum has been fantastic for keeping my skin hydrated and looking smoother!”Lilly Sky·“Good”ZuLaNi·“lightweight texture, skin doesn't feel greasy after use”Sarah Stewart·“Hydrating Peptide Serum That Makes Skin Feel Smoother”Cheesasaurus Rex·“Moisturizing”Level Up·“Nice and moisturizing”K·“Good for aging skin”C.A.H.·“Feels soothing and nourishing”SonomaGal·“Has a slight effect, so far.”Lance C.·
Fine lines & wrinkles serums
Skincare / Fine lines & wrinkles
Smooth the look of fine lines & wrinkles
Argireline™, Matrixyl 3000 and copper peptides for expression lines, crow’s feet and forehead lines.
Argireline™
Targets the look of dynamic expression lines
Matrixyl 3000
Supports smoother-looking skin over time
GHK-Cu
Copper peptide for a firmer, smoother look
Best for fine lines & wrinkles (5)
Targets dynamic expression lines
$39.00 30 mL
Helps reduce fine lines & wrinkles
$39.00 1 fl oz / 30 mL
5% PDRN for renewed-looking skin
$39.00 1 fl oz / 30 mL
Expression lines & barrier support
$39.00 1 fl oz / 30 mL
Hydration-first fine line care
$39.00 1 fl oz / 30 mL
The POISELLE Routine
Copper Peptide Serum$39.00 1 fl oz / 30 mL
10% Argireline Serum$39.00 30 mL
Matrixyl 3000 Serum$39.00 1 fl oz / 30 mL
PDRN Salmon DNA Serum$39.00 1 fl oz / 30 mL
Step
Firm & smooth
Expression lines
Hydrate
Night renewal
Use
AM & PM
AM & PM
AM & PM
PM, 2–3 nights a week to start
How to apply
A few drops on clean, dry skin. Massage onto face and neck.
Focus on forehead and around the eyes.
Massage onto face, neck and décolleté.
1–2 pumps after toning. Press into face and neck.
Why peptides
One routine, without the irritation
Peptides support a firmer, smoother look without the dryness and sensitivity many people get from strong actives.
| POISELLE Peptides | Retinol | Vitamin C | Basic moisturizer | |
|---|---|---|---|---|
| Gentle on sensitive skin | ✓ | ⊘ | Partial | ✓ |
| Supports a firmer look | ✓ | ✓ | Partial | ⊘ |
| Hydrates while it works | ✓ | ⊘ | ⊘ | ✓ |
| Daily AM & PM use | ✓ | ⊘ | ✓ | ✓ |
General comparison of ingredient types, for illustration.